Endocrine Abstracts

Introduction: Carcinoid tumors are included in the neuroendocrine tumor family. They are usually seen in the gastrointestinal tract and are asymptomatic unless liver metastases are present.Case Report: A 44-year-old male patient was admitted with chronic crampy abdominal pain, diarrhea, and redness of the face and neck. He was admitted to the emergency department for abdominal pain many times before and was hospitalized in the general surgery department ...

Aim: The purpose of this study was to analysis BRAF V600E mutational status in papillary thyroid microcarcinomas (PTMCs) and unknown malignant potential thyroid tumors (UMP-TTs) and to investigate association of BRAF V600 positivity with clinicopathologic parameters.Material and method: Seventy-two PTMC and 20 UMPTT tissues were included in this study. Genomic DNA was extracted from paraffin-embedded tumor tissue. The paraffin-embedded thyroid tumor samp...

Pituitary adenomas are the most common lesions of sellar cavity. The usual symptoms are associated with endocrine dysfunctions and mass effects. In this case, a 39 year old female presented with headache for one year and progressive blurred vision, nausea, vomiting for two days. Brain magnetic resonance imaging showed a 16×9 mm hemorrhagic macroadenoma in sellar cavity concordant with apoplexia and anterior pituitary hormone deficiency. The patient underwent transshphenoi...

Background & Aim: Adrenocortical carcinoma (ACC) is an extremely rare malignancy usually with poor outcomes, although the prognosis varies greatly depending on the initial tumor stage. Here we present clinical and outcome diversity of the patients in a single center.Methods: We retrospectively analyzed 16 patients with ACC diagnosed between 2000 and 2022. Demographical findings, hormonal status, radiological findings, ENSAT stage, weiss score and Ki6...

Hypertrophic osteoarthropathy (HOA) is a syndrome characterized with proliferation of bones at the distal parts of extremities. Clubbing, periostitis of tubular bones and non-inflammatory arthritis of lower extremities are commonly seen as a part of this syndrome.66 years old male patient was admitted to our hospital with painful swelling of his left lower extremity for 2 months. He denies any other systemic symptoms such as fever and weight loss. He had...

Introduction: The thyroid is generally resistant to infections due to its encapsulated location, high iodine concentration, hydrogen peroxide production, and high levels of blood and lymphoid circulation therefore acute suppurative thyroiditis is rarely seen. The most common agents are Staphilococcus and Streptococcus. In this case we present acute suppurative thyroiditis caused by Burkholdeira cepacia, that is a rare infectious agent in adults.Case: 34 ...

Introduction: Thyroglossal duct cyst (TDC) is a developmental abnormality of the thyroid gland. Malignancy arising from this duct is very rare. Due to embryological remnants of thyroid tissue located in the TDC, all malignant tumors which develop in the thyroid gland may also develop in the TDC. In case of malignancy, the most probable diagnosis is papillary thyroid carcinoma.Case report: We present a 27-year-old female patient complaining of a midline n...

Introduction: Glucocorticoids, even endogenous or exogenous, suppress the inflammatory response therefore they are the most preferred treatment options in inflammatory diseases. Persistent hypercortisolism induces lymphopenia and lymphoid tissue atrophy. Excessive endogenous hypercortisolism might mask the active inflammatory disease. Rebound immune modulation may occur after Cushing’s syndrome (CS) remission, leading to the new onset of autoimmune diseases.<p class="...

Introduction: Lymphocytic hypophysitis is a rare endocrine disease involving lymphocytic infiltration and chronic pituitary inflammation. It may result in significant morbidity by loss of pituitary functions and neurological deficits. Pituitary abscess is another rare disease which may be associated with underlying parasellar pathology. Here, we report a case of lymphocytic hypophysitis diagnosed with a pituitary abscess and recurrent suprasellar involvement after surgery....

Background: Acromegaly is associated with increased risk of coronary atherosclerosis and cardiovascular mortality. Changes in coagulation and fibrinolysis markers in acromegalic patients have been shown to indicate increase in the risk of developing cardiovascular disease. Mean platelet volume (MPV) is a marker of platelet functions and activity, and increased MPV is an independent risk factor of myocardial infarction and thrombotic events. In this study, we examined the level...